I've just recently wrapped up evaluation and testing of several enterprise antispyware applications.  Our main products of interest were McAfee's AntiSpyware Enterprise module for VirusScan Enterprise, Webroot's Spy Sweeper Enterprise, and Sunbelt's CounterSpy Enterprise.

In my testing, I found that the McAfee product's detection and removal capabilities left much to be desired... but Spy Sweeper Enterprise and CounterSpy Enterprise seemed rather close in detection and removal accuracy, with Spy Sweeper slightly edging out CounterSpy.

Despite this, we've made the decision to recommend CounterSpy.  I found the product to be extremely simple to administer, and as I'm a rather frequent reader of SunbeltBlog, I'm aware that there's a 2.0 release just around the corner which is only going to improve and already impressive product.

I'm interested to hear -- what product (or products) are you using in your environment to manage malicious software?  What would you recommend if you had to purchase an application now?